6OGJ

MeCP2 MBD in complex with DNA

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Methyl-CpG-binding protein 2	polymer	98	11179.5	2	UniProt (P51608) Pfam (PF01429)	Homo sapiens (Human)	MeCp2
2	C (D)	DNA (5'-D(*CP*GP*GP*AP*GP*TP*GP*TP*AP*GP*GP*C)-3')	polymer	12	3743.4	1		synthetic construct
3	D (C)	DNA (5'-D(*GP*CP*CP*TP*AP*CP*AP*CP*TP*CP*CP*G)-3')	polymer	12	3583.3	1		synthetic construct
4	E, F, G, H, I... (A, B, D, C)	UNKNOWN ATOM OR ION	non-polymer			8	Chemie (UNX)
5	M, N, O, P (A, B, D, C)	water	water		18.0	41	Chemie (HOH)

Sequence modifications

A, B: 77 - 166 (UniProt: P51608)

PDB	External Database	Details
Ala 167	-	expression tag
His 168	-	expression tag
His 169	-	expression tag
His 170	-	expression tag
His 171	-	expression tag
His 172	-	expression tag
His 173	-	expression tag
His 174	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	29685.8
Non-Polymers*	Number of molecules	8
	Total formula weight	0.0
All*	Total formula weight	29685.8

*Water molecules are not included.