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6OEV

Structure of human Patched1 in complex with native Sonic Hedgehog

Replaces:  6D4J
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Protein patched homolog 1polymer1447160714.41UniProt (Q13635)
Pfam (PF02460)
Homo sapiens (Human)PTC1
2B
(C)
Sonic hedgehog proteinpolymer17519832.41UniProt (Q15465)
Pfam (PF01085)
Homo sapiens (Human)SHH,HHG-1,Shh unprocessed N-terminal signaling and C-terminal autoprocessing domains,ShhNC
3C, D
(B, D)
2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranosebranched424.42In PDB
GlyTouCan (G42666HT)
4E, F
(A)
2-acetamido-2-deoxy-beta-D-glucopyranosenon-polymer221.22Chemie (NAG)
5G
(C)
ZINC IONnon-polymer65.41Chemie (ZN)
Sequence modifications
C: 23 - 197 (UniProt: Q15465)
PDBExternal DatabaseDetails
Plm 23Ala 23engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight180546.9
BranchedNumber of molecules2
Total formula weight848.8
Non-Polymers*Number of molecules3
Total formula weight507.8
All*Total formula weight181903.5
*Water molecules are not included.

237735

PDB entries from 2025-06-18

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