6OEN
Cryo-EM structure of mouse RAG1/2 PRC complex (DNA1)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, C) | V(D)J recombination-activating protein 1 | polymer | 1040 | 119388.4 | 2 | UniProt (P15919) Pfam (PF12560) Pfam (PF00097) Pfam (PF10426) Pfam (PF12940) | Mus musculus (Mouse) | RAG-1 |
| 2 | C, D (B, D) | V(D)J recombination-activating protein 2 | polymer | 527 | 59138.4 | 2 | UniProt (P21784) Pfam (PF03089) Pfam (PF13341) | Mus musculus (Mouse) | RAG-2 |
| 3 | E (G) | DNA (57-MER) | polymer | 61 | 18809.0 | 1 | Escherichia coli K-12 | ||
| 4 | F (I) | DNA (46-MER) | polymer | 50 | 15275.8 | 1 | Escherichia coli K-12 | ||
| 5 | G (F) | DNA (46-MER) | polymer | 50 | 15528.9 | 1 | Escherichia coli K-12 | ||
| 6 | H (J) | DNA (57-MER) | polymer | 61 | 18792.1 | 1 | Escherichia coli K-12 | ||
| 7 | I, J (N, H) | High mobility group protein B1 | polymer | 163 | 18897.9 | 2 | UniProt (P09429) Pfam (PF09011) Pfam (PF00505) | Homo sapiens (Human) | High mobility group protein 1,HMG-1 |
| 8 | K, M (A, C) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 9 | L (A) | CALCIUM ION | non-polymer | 40.1 | 1 | Chemie (CA) |
Sequence modifications
A, C: 1 - 1040 (UniProt: P15919)
| PDB | External Database | Details |
|---|---|---|
| Gln 962 | Glu 962 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 10 |
| Total formula weight | 463255.2 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 170.9 | |
| All* | Total formula weight | 463426.0 |
