6OE4
Prefusion RSV F monomer bound by neutralizing antibody CR9501
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, D | Fusion glycoprotein F0 | polymer | 521 | 57943.5 | 2 | UniProt (P03420) Pfam (PF00523) In PDB | Human respiratory syncytial virus A (strain A2) | Protein F, Prefusion RSV F |
2 | C, F | CR9501 Fab Light Chain | polymer | 214 | 23557.1 | 2 | Homo sapiens | ||
3 | B, E | CR9501 Fab Heavy Chain | polymer | 230 | 24367.3 | 2 | Homo sapiens | ||
4 | D, C, F | 1,2-ETHANEDIOL | non-polymer | 62.1 | 5 | Chemie (EDO) |
Sequence modifications
A, D: 1 - 513 (UniProt: P03420)
PDB | External Database | Details |
---|---|---|
Ala 102 | Pro 102 | conflict |
Cys 155 | Ser 155 | engineered mutation |
Phe 190 | Ser 190 | engineered mutation |
Leu 207 | Val 207 | engineered mutation |
Cys 290 | Ser 290 | engineered mutation |
Val 379 | Ile 379 | conflict |
Val 447 | Met 447 | conflict |
Gly 514 | - | expression tag |
Ser 515 | - | expression tag |
Leu 516 | - | expression tag |
Glu 517 | - | expression tag |
Val 518 | - | expression tag |
Leu 519 | - | expression tag |
Phe 520 | - | expression tag |
Gln 521 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 6 |
Total formula weight | 211735.6 | |
Non-Polymers* | Number of molecules | 5 |
Total formula weight | 310.3 | |
All* | Total formula weight | 212046.0 |