6O9Y
Structure of human PARG complexed with JA2-8
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Poly(ADP-ribose) glycohydrolase | polymer | 533 | 61223.6 | 1 | UniProt (Q86W56) Pfam (PF20811) Pfam (PF05028) | Homo sapiens (Human) | |
| 2 | B (A) | 7-[(2S)-2-hydroxy-3-(morpholin-4-yl)propyl]-1,3-dimethyl-3,7-dihydro-1H-purine-2,6-dione | non-polymer | 323.3 | 1 | Chemie (M0V) | |||
| 3 | C (A) | water | water | 18.0 | 224 | Chemie (HOH) |
Sequence modifications
A: 448 - 976 (UniProt: Q86W56)
| PDB | External Database | Details |
|---|---|---|
| Gly 444 | - | expression tag |
| Pro 445 | - | expression tag |
| His 446 | - | expression tag |
| Met 447 | - | expression tag |
| Ala 616 | Lys 616 | engineered mutation |
| Ala 617 | Gln 617 | engineered mutation |
| Ala 618 | Lys 618 | engineered mutation |
| Ala 688 | Glu 688 | engineered mutation |
| Ala 689 | Lys 689 | engineered mutation |
| Ala 690 | Lys 690 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 61223.6 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 323.3 | |
| All* | Total formula weight | 61547.0 |
