6O69
Crystal Structure of Double Mutant L380R/F535K of Human Acetylcholinesterase
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Acetylcholinesterase | polymer | 542 | 59473.2 | 1 | UniProt (P22303) Pfam (PF00135) In PDB | Homo sapiens (Human) | AChE |
| 2 | B | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 570.5 | 1 | In PDB GlyTouCan (G21290RB) | |||
| 3 | water | water | 18.0 | 259 | Chemie (HOH) |
Sequence modifications
A: 2 - 543 (UniProt: P22303)
| PDB | External Database | Details |
|---|---|---|
| Arg 380 | Leu 411 | engineered mutation |
| Lys 535 | Phe 566 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 59473.2 | |
| Branched | Number of molecules | 1 |
| Total formula weight | 570.5 | |
| All* | Total formula weight | 60043.7 |
