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6O5V

Binary complex of native hAChE with oxime reactivator RS-170B

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Acetylcholinesterasepolymer55060288.02UniProt (P22303)
Pfam (PF00135)
Homo sapiens (Human)AChE
2C, H
(A, B)
4-carbamoyl-1-(3-{2-[(E)-(hydroxyimino)methyl]-1H-imidazol-1-yl}propyl)pyridin-1-iumnon-polymer274.32Chemie (LND)
3D, E
(A)
NITRATE IONnon-polymer62.02Chemie (NO3)
4F, G, I, J
(A, B)
GLYCEROLnon-polymer92.14Chemie (GOL)
5K, L
(A, B)
waterwater18.0921Chemie (HOH)
Sequence modifications
A, B: 1 - 547 (UniProt: P22303)
PDBExternal DatabaseDetails
Gly -2-expression tag
Pro -1-expression tag
Leu 0-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight120576.0
Non-Polymers*Number of molecules8
Total formula weight1041.0
All*Total formula weight121616.9
*Water molecules are not included.

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PDB entries from 2025-12-24

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