6O5E

Crystal structure of the Vitronectin hemopexin-like domain

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Vitronectin	polymer	204	23436.2	2	UniProt (P04004) Pfam (PF00045) In PDB	Homo sapiens (Human)	VN, S-protein, Serum-spreading factor, V75
2	A, B	SODIUM ION	non-polymer		23.0	4	Chemie (NA)
3	A, B	CHLORIDE ION	non-polymer		35.5	2	Chemie (CL)
4	A, B	SULFATE ION	non-polymer		96.1	3	Chemie (SO4)
5	A	IMIDAZOLE	non-polymer		69.1	1	Chemie (IMD)
6	B	NITRATE ION	non-polymer		62.0	1	Chemie (NO3)
7		water	water		18.0	168	Chemie (HOH)

Sequence modifications

A, B: 154 - 323 (UniProt: P04004)

PDB	External Database	Details
Met 153	-	initiating methionine
Ser 180	Cys 180	engineered mutation
Ser 215	Cys 215	engineered mutation

A, B: 324 - 354 (UniProt: P04004)
A, B: 435 - 474 (UniProt: P04004)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	46872.4
Non-Polymers*	Number of molecules	11
	Total formula weight	582.1
All*	Total formula weight	47454.5

*Water molecules are not included.