6O4G
Structure of ALDH7A1 mutant P169S complexed with alpha-aminoadipate
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (A, B, C, D, E...) | Alpha-aminoadipic semialdehyde dehydrogenase | polymer | 513 | 55610.3 | 8 | UniProt (P49419) Pfam (PF00171) | Homo sapiens (Human) | Alpha-AASA dehydrogenase,Aldehyde dehydrogenase family 7 member A1,Antiquitin-1,Betaine aldehyde dehydrogenase,Delta1-piperideine-6-carboxylate dehydrogenase,P6c dehydrogenase, ALDH7A1 |
| 2 | I, J, K, L (B, E, G, H) | 2-AMINOHEXANEDIOIC ACID | non-polymer | 161.2 | 4 | Chemie (UN1) | |||
| 3 | M, N, O, P, Q... (A, B, C, D, E...) | water | water | 18.0 | 951 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E, F, G, H: 1 - 511 (UniProt: P49419)
| PDB | External Database | Details |
|---|---|---|
| Gly -1 | - | expression tag |
| His 0 | - | expression tag |
| Ser 169 | Pro 197 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 444882.6 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 644.6 | |
| All* | Total formula weight | 445527.2 |
