6O4E
Structure of ALDH7A1 mutant N167S complexed with NAD
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (A, B, C, D, E...) | Alpha-aminoadipic semialdehyde dehydrogenase | polymer | 513 | 55593.3 | 8 | UniProt (P49419) Pfam (PF00171) | Homo sapiens (Human) | Alpha-AASA dehydrogenase,Aldehyde dehydrogenase family 7 member A1,Antiquitin-1,Betaine aldehyde dehydrogenase,Delta1-piperideine-6-carboxylate dehydrogenase,P6c dehydrogenase,ALDH7A1 |
| 2 | BA, I, K, N, Q... (H, A, B, C, D...) | NICOTINAMIDE-ADENINE-DINUCLEOTIDE | non-polymer | 663.4 | 8 | Chemie (NAD) | |||
| 3 | J, R, U (A, D, E) | TETRAETHYLENE GLYCOL | non-polymer | 194.2 | 3 | Chemie (PG4) | |||
| 4 | CA, L, O, Z (H, B, C, G) | PENTAETHYLENE GLYCOL | non-polymer | 238.3 | 4 | Chemie (1PE) | |||
| 5 | AA, DA, M, P, S... (G, H, B, C, D...) | MAGNESIUM ION | non-polymer | 24.3 | 6 | Chemie (MG) | |||
| 6 | W (F) | HEXAETHYLENE GLYCOL | non-polymer | 282.3 | 1 | Chemie (P6G) | |||
| 7 | EA, FA, GA, HA, IA... (A, B, C, D, E...) | water | water | 18.0 | 2046 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E, F, G, H: 1 - 511 (UniProt: P49419)
| PDB | External Database | Details |
|---|---|---|
| Gly -1 | - | expression tag |
| His 0 | - | expression tag |
| Ser 167 | Asn 195 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 444746.8 | |
| Non-Polymers* | Number of molecules | 22 |
| Total formula weight | 7271.4 | |
| All* | Total formula weight | 452018.1 |
