6O46
Crystal structure of human KRAS P34R mutant in complex with GNP and Phosphate
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | GTPase KRas | polymer | 169 | 19259.7 | 3 | UniProt (P01116) Pfam (PF00071) | Homo sapiens (Human) | K-Ras 2,Ki-Ras,c-K-ras,c-Ki-ras |
| 2 | D, G, I (A, B, C) | PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER | non-polymer | 522.2 | 3 | Chemie (GNP) | |||
| 3 | E, H, J (A, B, C) | MAGNESIUM ION | non-polymer | 24.3 | 3 | Chemie (MG) | |||
| 4 | F (A) | PHOSPHATE ION | non-polymer | 95.0 | 1 | Chemie (PO4) | |||
| 5 | K, L, M (A, B, C) | water | water | 18.0 | 386 | Chemie (HOH) |
Sequence modifications
A, B, C: 1 - 168 (UniProt: P01116)
| PDB | External Database | Details |
|---|---|---|
| Gly 0 | - | expression tag |
| Arg 34 | Pro 34 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 57779.1 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 1734.5 | |
| All* | Total formula weight | 59513.6 |
