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6O3B

Crystal structure of Frizzled 7 CRD in complex with F6 Fab

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, D
(A, E)
Antibody Fab F6, Light chainpolymer21423360.92Homo sapiens
2B, E
(B, G)
Antibody Fab F6, Heavy chainpolymer22123402.02Homo sapiens
3C, F
(C, H)
Frizzled-7polymer14015215.22UniProt (O75084)
Pfam (PF01392)
Homo sapiens (Human)hFz7,FzE3
4G, H, J, K, M
(B, C, G, H)
GLYCEROLnon-polymer92.15Chemie (GOL)
5I, L
(C, H)
2-acetamido-2-deoxy-beta-D-glucopyranosenon-polymer221.22Chemie (NAG)
6N, O, P, Q, R...
(A, B, C, E, G...)
waterwater18.0163Chemie (HOH)
Sequence modifications
C, H: 42 - 179 (UniProt: O75084)
PDBExternal DatabaseDetails
Thr 40-expression tag
Gly 41-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains6
Total formula weight123956.4
Non-Polymers*Number of molecules7
Total formula weight902.9
All*Total formula weight124859.3
*Water molecules are not included.

246031

PDB entries from 2025-12-10

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