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6O21

Crystal Structure of Human KLK4 in Complex With Cleaved SFTI-FCQR(Asn14)[1,14] Inhibitor

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Kallikrein 4 (Prostase, enamel matrix, prostate), isoform CRA_apolymer22323926.01UniProt (A0A0C4DFQ5)
Pfam (PF00089)
UniProt (by SIFTS) (Q9Y5K2)
Homo sapiens (Human)Kallikrein B1,Kallikrein-4
2B
(B)
Trypsin inhibitor 1polymer141579.91BIRD (PRD_001059)Helianthus annuusacyclic SFTI-FCQR(Asn14)
3C, D, E
(A)
SULFATE IONnon-polymer96.13Chemie (SO4)
4F
(A)
(4S)-2-METHYL-2,4-PENTANEDIOLnon-polymer118.21Chemie (MPD)
5G, H
(A, B)
waterwater18.0238Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight25505.9
Non-Polymers*Number of molecules4
Total formula weight406.4
All*Total formula weight25912.2
*Water molecules are not included.

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PDB entries from 2025-06-18

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