6O1B
Crystal structure of the TIR domain G601P mutant from human SARM1, crystal form 1
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Sterile alpha and TIR motif-containing protein 1 | polymer | 144 | 16373.8 | 1 | UniProt (Q6SZW1) Pfam (PF13676) | Homo sapiens (Human) | Sterile alpha and Armadillo repeat protein,Sterile alpha motif domain-containing protein 2,SAM domain-containing protein 2,Tir-1 homolog |
| 2 | B (A) | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID | non-polymer | 195.2 | 1 | Chemie (MES) | |||
| 3 | C (A) | water | water | 18.0 | 131 | Chemie (HOH) |
Sequence modifications
A: 560 - 700 (UniProt: Q6SZW1)
| PDB | External Database | Details |
|---|---|---|
| Ser 557 | - | expression tag |
| Asn 558 | - | expression tag |
| Ala 559 | - | expression tag |
| Pro 601 | Gly 601 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 16373.8 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 195.2 | |
| All* | Total formula weight | 16569.0 |
