6O0V
Crystal structure of the TIR domain G601P mutant from human SARM1, crystal form 2
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C, D | Sterile alpha and TIR motif-containing protein 1 | polymer | 144 | 16373.8 | 4 | UniProt (Q6SZW1) Pfam (PF13676) In PDB | Homo sapiens (Human) | Sterile alpha and Armadillo repeat protein,Sterile alpha motif domain-containing protein 2,SAM domain-containing protein 2,Tir-1 homolog |
2 | A, B, D | CHLORIDE ION | non-polymer | 35.5 | 3 | Chemie (CL) | |||
3 | C | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID | non-polymer | 195.2 | 1 | Chemie (MES) | |||
4 | water | water | 18.0 | 228 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 560 - 700 (UniProt: Q6SZW1)
PDB | External Database | Details |
---|---|---|
Ser 557 | - | expression tag |
Asn 558 | - | expression tag |
Ala 559 | - | expression tag |
Pro 601 | Gly 601 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 65495.1 | |
Non-Polymers* | Number of molecules | 4 |
Total formula weight | 301.6 | |
All* | Total formula weight | 65796.7 |