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6O0U

Crystal structure of the TIR domain H685A mutant from human SARM1

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Sterile alpha and TIR motif-containing protein 1polymer14416266.62UniProt (Q6SZW1)
Pfam (PF13676)
Homo sapiens (Human)Sterile alpha and Armadillo repeat protein,Sterile alpha motif domain-containing protein 2,SAM domain-containing protein 2,Tir-1 homolog
Sequence modifications
A, B: 560 - 700 (UniProt: Q6SZW1)
PDBExternal DatabaseDetails
Ser 557-expression tag
Asn 558-expression tag
Ala 559-expression tag
Ala 685His 685engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight32533.3
All*Total formula weight32533.3
*Water molecules are not included.

250059

PDB entries from 2026-03-04

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