6O0Q
Crystal structure of the TIR domain from human SARM1 in complex with ribose
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Sterile alpha and TIR motif-containing protein 1 | polymer | 144 | 16333.7 | 2 | UniProt (Q6SZW1) Pfam (PF13676) | Homo sapiens (Human) | Sterile alpha and Armadillo repeat protein,Sterile alpha motif domain-containing protein 2,SAM domain-containing protein 2,Tir-1 homolog |
| 2 | C, E (A, B) | beta-D-ribofuranose | non-polymer | 150.1 | 2 | Chemie (BDR) | |||
| 3 | D, F (A, B) | CHLORIDE ION | non-polymer | 35.5 | 2 | Chemie (CL) | |||
| 4 | G, H (A, B) | water | water | 18.0 | 170 | Chemie (HOH) |
Sequence modifications
A, B: 560 - 700 (UniProt: Q6SZW1)
| PDB | External Database | Details |
|---|---|---|
| Ser 557 | - | expression tag |
| Asn 558 | - | expression tag |
| Ala 559 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 32667.4 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 371.2 | |
| All* | Total formula weight | 33038.6 |
