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6NZW

LRRC8A-DCPIB in MSP1E3D1 nanodisc constricted state

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, D, E...Volume-regulated anion channel subunit LRRC8Apolymer82095314.66UniProt (Q80WG5)
Pfam (PF12534)
Pfam (PF13855)
In PDB
Mus musculus (Mouse)Leucine-rich repeat-containing protein 8A
2A, B, C, D, E...(2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphatenon-polymer760.118Chemie (POV)
3A4-{[(2S)-2-butyl-6,7-dichloro-2-cyclopentyl-1-oxo-2,3-dihydro-1H-inden-5-yl]oxy}butanoic acidnon-polymer427.41Chemie (L9Y)
Sequence modifications
A, B, C, D, E, F: 1 - 810 (UniProt: Q80WG5)
PDBExternal DatabaseDetails
Ser 811-expression tag
Asn 812-expression tag
Ser 813-expression tag
Leu 814-expression tag
Glu 815-expression tag
Val 816-expression tag
Leu 817-expression tag
Phe 818-expression tag
Gln 819-expression tag
Gly 820-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains6
Total formula weight571887.4
Non-Polymers*Number of molecules19
Total formula weight14108.7
All*Total formula weight585996.1
*Water molecules are not included.

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PDB entries from 2024-07-10

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