6NYV
Structure of spastin AAA domain in complex with a quinazoline-based inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (B) | Spastin | polymer | 314 | 34321.0 | 1 | UniProt (Q8I0P1) Pfam (PF00004) Pfam (PF17862) Pfam (PF09336) | Drosophila melanogaster (Fruit fly) | D-Spastin,Dm-Spastin,Dspastin |
| 2 | B (B) | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 3 | C (B) | N-(3-tert-butyl-1H-pyrazol-5-yl)-2-[(2R)-2-methylpiperazin-1-yl]quinazolin-4-amine | non-polymer | 365.5 | 1 | Chemie (LBD) | |||
| 4 | D (B) | (4S)-2-METHYL-2,4-PENTANEDIOL | non-polymer | 118.2 | 1 | Chemie (MPD) | |||
| 5 | E (B) | water | water | 18.0 | 58 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 34321.0 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 579.7 | |
| All* | Total formula weight | 34900.7 |
