6NY7
Crystal Structure of NDM-1 D199N with Compound 16
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Carbapenem Hydrolyzing Class B Metallo beta lactamase NDM-1 | polymer | 233 | 24601.7 | 1 | UniProt (E9NWK5) Pfam (PF00753) UniProt (by SIFTS) (C7C422) | Klebsiella pneumoniae | Metallo beta-lactamase,Metallo-beta-lactamase NDM-1,NDM-1 metallo-beta-lactamase,NDM1 metallo-beta-lactamase,New Delhi Metallo carbapenemase-1,New Delhi metallo-beta-lactamase NDM-1,New Delhi metallo-beta-lactamse 1,Subclass B1 metallo-beta-lactamase NDM-1 |
| 2 | B, C (A) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 3 | D (A) | [(5,7-dibromo-2-oxo-1,2-dihydroquinolin-4-yl)methyl]phosphonic acid | non-polymer | 397.0 | 1 | Chemie (L8J) | |||
| 4 | E (A) | water | water | 18.0 | 291 | Chemie (HOH) |
Sequence modifications
A: 42 - 270 (UniProt: E9NWK5)
| PDB | External Database | Details |
|---|---|---|
| Gly 38 | - | expression tag |
| Ser 39 | - | expression tag |
| His 40 | - | expression tag |
| Met 41 | - | expression tag |
| Asn 199 | Asp 199 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 24601.7 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 527.8 | |
| All* | Total formula weight | 25129.5 |
