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6NVH

FGFR4 complex with N-(2-((5-((2,6-dichloro-3,5-dimethoxybenzyl)oxy)pyrimidin-2-yl)amino)-3-methylphenyl)acrylamide

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1AFibroblast growth factor receptor 4polymer30033867.21UniProt (P22455)
Pfam (PF07714)
In PDB
Homo sapiens (Human)FGFR-4
2ASULFATE IONnon-polymer96.12Chemie (SO4)
3AN-[2-({5-[(2,6-dichloro-3,5-dimethoxyphenyl)methoxy]pyrimidin-2-yl}amino)-3-methylphenyl]propanamidenon-polymer491.41Chemie (XL6)
4waterwater18.0106Chemie (HOH)
Sequence modifications
A: 450 - 742 (UniProt: P22455)
PDBExternal DatabaseDetails
Met 449-expression tag
-Pro 570deletion
-Asp 571deletion
-Leu 572deletion
-Ser 573deletion
-Pro 574deletion
-Asp 575deletion
-Gly 576deletion
-Pro 577deletion
-Arg 578deletion
His 743-expression tag
His 744-expression tag
His 745-expression tag
His 746-expression tag
His 747-expression tag
His 748-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight33867.2
Non-Polymers*Number of molecules3
Total formula weight683.5
All*Total formula weight34550.7
*Water molecules are not included.

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PDB entries from 2024-07-31

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