6NVG
FGFR4 complex with N-(3,5-dichloro-2-((5-((2,6-dichloro-3,5-dimethoxybenzyl)oxy)pyrimidin-2-yl)amino)phenyl)acrylamide
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Fibroblast growth factor receptor 4 | polymer | 300 | 33867.2 | 1 | UniProt (P22455) Pfam (PF07714) In PDB | Homo sapiens (Human) | FGFR-4 |
2 | A | SULFATE ION | non-polymer | 96.1 | 3 | Chemie (SO4) | |||
3 | A | N-[3,5-dichloro-2-({5-[(2,6-dichloro-3,5-dimethoxyphenyl)methoxy]pyrimidin-2-yl}amino)phenyl]propanamide | non-polymer | 546.2 | 1 | Chemie (XL8) | |||
4 | water | water | 18.0 | 76 | Chemie (HOH) |
Sequence modifications
A: 450 - 742 (UniProt: P22455)
PDB | External Database | Details |
---|---|---|
Met 449 | - | expression tag |
- | Pro 570 | deletion |
- | Asp 571 | deletion |
- | Leu 572 | deletion |
- | Ser 573 | deletion |
- | Pro 574 | deletion |
- | Asp 575 | deletion |
- | Gly 576 | deletion |
- | Pro 577 | deletion |
- | Arg 578 | deletion |
His 743 | - | expression tag |
His 744 | - | expression tag |
His 745 | - | expression tag |
His 746 | - | expression tag |
His 747 | - | expression tag |
His 748 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 33867.2 | |
Non-Polymers* | Number of molecules | 4 |
Total formula weight | 834.4 | |
All* | Total formula weight | 34701.6 |