6NT7

Cryo-EM structure of full-length chicken STING in the cGAMP-bound dimeric state

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Stimulator of interferon genes protein	polymer	392	44207.1	2	UniProt (A0A1D5P7Q9) Pfam (PF15009) UniProt (by SIFTS) (E1C7U0) In PDB	Gallus gallus (Chicken)
2	A	cGAMP	non-polymer		674.4	1	Chemie (1SY)

Sequence modifications

A, B: 1 - 379 (UniProt: A0A1D5P7Q9)

PDB	External Database	Details
Gly 380	-	expression tag
Ile 381	-	expression tag
His 382	-	expression tag
Arg 383	-	expression tag
Pro 384	-	expression tag
Asp 385	-	expression tag
Tyr 386	-	expression tag
Lys 387	-	expression tag
Asp 388	-	expression tag
Asp 389	-	expression tag
Asp 390	-	expression tag
Asp 391	-	expression tag
Lys 392	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	88414.1
Non-Polymers*	Number of molecules	1
	Total formula weight	674.4
All*	Total formula weight	89088.6

*Water molecules are not included.