6NT7
Cryo-EM structure of full-length chicken STING in the cGAMP-bound dimeric state
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Stimulator of interferon genes protein | polymer | 392 | 44207.1 | 2 | UniProt (A0A1D5P7Q9) Pfam (PF15009) UniProt (by SIFTS) (E1C7U0) | Gallus gallus (Chicken) | |
| 2 | C (A) | cGAMP | non-polymer | 674.4 | 1 | Chemie (1SY) |
Sequence modifications
A, B: 1 - 379 (UniProt: A0A1D5P7Q9)
| PDB | External Database | Details |
|---|---|---|
| Gly 380 | - | expression tag |
| Ile 381 | - | expression tag |
| His 382 | - | expression tag |
| Arg 383 | - | expression tag |
| Pro 384 | - | expression tag |
| Asp 385 | - | expression tag |
| Tyr 386 | - | expression tag |
| Lys 387 | - | expression tag |
| Asp 388 | - | expression tag |
| Asp 389 | - | expression tag |
| Asp 390 | - | expression tag |
| Asp 391 | - | expression tag |
| Lys 392 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 88414.1 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 674.4 | |
| All* | Total formula weight | 89088.6 |
