6NSC

Crystal structure of the A/Brisbane/10/2007 (H3N2) influenza virus hemagglutinin G186V/L194P mutant apo form

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Hemagglutinin HA1 chain	polymer	321	35763.3	1	UniProt (A8W893) Pfam (PF00509) In PDB	Influenza A virus (A/Brisbane/10/2007(H3N2))
2	B	Hemagglutinin HA2 chain	polymer	176	20109.4	1	UniProt (A8W891) Pfam (PF00509) In PDB	Influenza A virus
3	C	alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		910.8	1	In PDB GlyTouCan (G22768VO)
4	D	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[beta-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose	branched		570.5	1	In PDB GlyTouCan (G28454KX)
5	E, F	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		424.4	2	In PDB GlyTouCan (G42666HT)
6	A	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	2	Chemie (NAG)
7		water	water		18.0	240	Chemie (HOH)

Sequence modifications

A: 11 - 329 (UniProt: A8W893)

PDB	External Database	Details
Pro 9	-	expression tag
Gly 10	-	expression tag
Val 186	Gly 186	engineered mutation
Pro 194	Leu 194	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	55872.7
Branched	Number of molecules	4
	Total formula weight	2330.2
Non-Polymers*	Number of molecules	2
	Total formula weight	442.4
All*	Total formula weight	58645.3

*Water molecules are not included.