6NNV
PD-L1 IgV domain complex with macro-cyclic peptide
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C, D | Programmed cell death 1 ligand 1 | polymer | 127 | 14542.6 | 4 | UniProt (Q9NZQ7) Pfam (PF07686) In PDB | Homo sapiens (Human) | Programmed death ligand 1,B7 homolog 1,B7-H1 |
2 | I, J, K, L | macrocyclic peptide | polymer | 16 | 1853.2 | 4 | synthetic construct | ||
3 | water | water | 18.0 | 278 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 18 - 134 (UniProt: Q9NZQ7)
PDB | External Database | Details |
---|---|---|
Thr 76 | Val 76 | engineered mutation |
Ala 135 | - | expression tag |
Ala 136 | - | expression tag |
Ala 137 | - | expression tag |
Leu 138 | - | expression tag |
His 139 | - | expression tag |
Glu 140 | - | expression tag |
His 141 | - | expression tag |
His 142 | - | expression tag |
His 143 | - | expression tag |
His 144 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 8 |
Total formula weight | 65583.3 | |
All* | Total formula weight | 65583.3 |