6NNV

PD-L1 IgV domain complex with macro-cyclic peptide

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	Programmed cell death 1 ligand 1	polymer	127	14542.6	4	UniProt (Q9NZQ7) Pfam (PF07686)	Homo sapiens (Human)	Programmed death ligand 1,B7 homolog 1,B7-H1
2	E, F, G, H (I, J, K, L)	macrocyclic peptide	polymer	16	1853.2	4		synthetic construct
3	I, J, K, L, M... (A, B, C, D, I...)	water	water		18.0	278	Chemie (HOH)

Sequence modifications

A, B, C, D: 18 - 134 (UniProt: Q9NZQ7)

PDB	External Database	Details
Thr 76	Val 76	engineered mutation
Ala 135	-	expression tag
Ala 136	-	expression tag
Ala 137	-	expression tag
Leu 138	-	expression tag
His 139	-	expression tag
Glu 140	-	expression tag
His 141	-	expression tag
His 142	-	expression tag
His 143	-	expression tag
His 144	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	8
	Total formula weight	65583.3
All*	Total formula weight	65583.3

*Water molecules are not included.