6NNE
Crystal structure of Dihydrofolate reductase from Mycobacterium tuberculosis in complex with diaverdine
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Dihydrofolate reductase | polymer | 159 | 17661.0 | 2 | UniProt (A5U6B6) Pfam (PF00186) | Mycobacterium tuberculosis (strain ATCC 25177 / H37Ra) | |
| 2 | C, H (A, B) | COBALT (II) ION | non-polymer | 58.9 | 2 | Chemie (CO) | |||
| 3 | D, I (A, B) | NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | non-polymer | 745.4 | 2 | Chemie (NDP) | |||
| 4 | E, J (A, B) | 5-[(3,4-dimethoxyphenyl)methyl]pyrimidine-2,4-diamine | non-polymer | 260.3 | 2 | Chemie (KUP) | |||
| 5 | F, G, K, L (A, B) | SULFATE ION | non-polymer | 96.1 | 4 | Chemie (SO4) | |||
| 6 | M, N (A, B) | water | water | 18.0 | 239 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 35322.0 | |
| Non-Polymers* | Number of molecules | 10 |
| Total formula weight | 2513.5 | |
| All* | Total formula weight | 37835.5 |
