6NM8

IgV-V76T BMS compound 105

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Programmed cell death 1 ligand 1	polymer	129	14811.9	2	UniProt (Q9NZQ7) Pfam (PF07686)	Homo sapiens (Human)	Programmed death ligand 1,B7 homolog 1,B7-H1
2	C (A)	N-({2,6-dimethoxy-4-[(2-methyl[1,1'-biphenyl]-3-yl)methoxy]phenyl}methyl)-D-alanine	non-polymer		435.5	1	Chemie (KSD)

Sequence modifications

A, B: 19 - 134 (UniProt: Q9NZQ7)

PDB	External Database	Details
Met 17	-	initiating methionine
Ala 18	-	expression tag
Thr 76	Val 76	engineered mutation
Ala 135	-	expression tag
Ala 136	-	expression tag
Ala 137	-	expression tag
Leu 138	-	expression tag
Glu 139	-	expression tag
His 140	-	expression tag
His 141	-	expression tag
His 142	-	expression tag
His 143	-	expression tag
His 144	-	expression tag
His 145	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	29623.9
Non-Polymers*	Number of molecules	1
	Total formula weight	435.5
All*	Total formula weight	30059.4

*Water molecules are not included.