6NLA
Crystal structure of de novo designed metal-controlled dimer of B1 immunoglobulin-binding domain of Streptococcal Protein G (L12H, E15V, T16L, T18I, V29H, Y33H, N37L)-zinc
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Immunoglobulin G-binding protein G | polymer | 56 | 6233.9 | 1 | UniProt (P19909) Pfam (PF01378) | Streptococcus | IgG-binding protein G |
| 2 | B, C (A) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 3 | D, E, G (A) | CHLORIDE ION | non-polymer | 35.5 | 3 | Chemie (CL) | |||
| 4 | F (A) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 5 | H, I (A) | SODIUM ION | non-polymer | 23.0 | 2 | Chemie (NA) | |||
| 6 | J (A) | water | water | 18.0 | 113 | Chemie (HOH) |
Sequence modifications
A: 2 - 56 (UniProt: P19909)
| PDB | External Database | Details |
|---|---|---|
| Met 1 | - | initiating methionine |
| His 12 | Leu 313 | engineered mutation |
| Val 15 | Glu 316 | engineered mutation |
| Leu 16 | Thr 317 | engineered mutation |
| Ile 18 | Thr 319 | engineered mutation |
| His 29 | Val 330 | engineered mutation |
| His 33 | Tyr 334 | engineered mutation |
| Leu 37 | Asn 338 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 6233.9 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 375.3 | |
| All* | Total formula weight | 6609.2 |
