6NL5
Crystal structure of Mycobacterium tuberculosis dethiobiotin synthetase in complex with 2'-deoxycytidine triphosphate
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | ATP-dependent dethiobiotin synthetase BioD | polymer | 233 | 23285.7 | 4 | UniProt (P9WPQ5) Pfam (PF13500) | Mycobacterium tuberculosis H37Rv | DTB synthetase,DTBS,Dethiobiotin synthase |
| 2 | E, G, I, K (A, B, C, D) | 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE | non-polymer | 467.2 | 4 | Chemie (DCP) PubChem (44119993) PubChem (65091) PubChem (46936621) PubChem (53393445) PubChem (57187895) PubChem (472334) PubChem (625) PubChem (92436637) PubChem (92449132) PubChem (92449133) PubChem (121522025) PubChem (171699322) PubChem (129069886) | |||
| 3 | F, H, J, L (A, B, C, D) | MAGNESIUM ION | non-polymer | 24.3 | 4 | Chemie (MG) PubChem (888) | |||
| 4 | M, N, O, P (A, B, C, D) | water | water | 18.0 | 171 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 2 - 226 (UniProt: P9WPQ5)
| PDB | External Database | Details |
|---|---|---|
| His -6 | - | expression tag |
| His -5 | - | expression tag |
| His -4 | - | expression tag |
| His -3 | - | expression tag |
| His -2 | - | expression tag |
| His -1 | - | expression tag |
| Gly 0 | - | expression tag |
| Gly 1 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 93142.7 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 1965.8 | |
| All* | Total formula weight | 95108.5 |
