6NKU
Ternary complex crystal structure of DNA polymerase Beta with "hot-spot sequence" with dGTP
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A (T) | DNA (5'-D(*CP*CP*GP*AP*AP*CP*AP*AP*GP*CP*AP*TP*CP*AP*GP*C)-3') | polymer | 16 | 4861.2 | 1 | Homo sapiens | ||
2 | B (P) | DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*TP*(2DT))-3') | polymer | 10 | 3035.0 | 1 | Homo sapiens | ||
3 | C (D) | DNA (5'-D(P*TP*TP*CP*GP*G)-3') | polymer | 5 | 1511.0 | 1 | Homo sapiens | ||
4 | D (A) | DNA polymerase beta | polymer | 335 | 38241.7 | 1 | UniProt (P06746) Pfam (PF14716) Pfam (PF10391) Pfam (PF14792) Pfam (PF14791) | Homo sapiens (Human) | |
5 | E, H (T, A) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
6 | F, G, I (P, D, A) | SODIUM ION | non-polymer | 23.0 | 3 | Chemie (NA) | |||
7 | J, K, L, M (A) | CHLORIDE ION | non-polymer | 35.5 | 4 | Chemie (CL) | |||
8 | N (A) | 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE | non-polymer | 507.2 | 1 | Chemie (DGT) | |||
9 | O, P, Q, R (T, P, D, A) | water | water | 18.0 | 394 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 47648.9 | |
Non-Polymers* | Number of molecules | 10 |
Total formula weight | 766.6 | |
All* | Total formula weight | 48415.5 |