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6NKU

Ternary complex crystal structure of DNA polymerase Beta with "hot-spot sequence" with dGTP

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(T)
DNA (5'-D(*CP*CP*GP*AP*AP*CP*AP*AP*GP*CP*AP*TP*CP*AP*GP*C)-3')polymer164861.21Homo sapiens
2B
(P)
DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*TP*(2DT))-3')polymer103035.01Homo sapiens
3C
(D)
DNA (5'-D(P*TP*TP*CP*GP*G)-3')polymer51511.01Homo sapiens
4D
(A)
DNA polymerase betapolymer33538241.71UniProt (P06746)
Pfam (PF14716)
Pfam (PF10391)
Pfam (PF14792)
Pfam (PF14791)
Homo sapiens (Human)
5E, H
(T, A)
MAGNESIUM IONnon-polymer24.32Chemie (MG)
6F, G, I
(P, D, A)
SODIUM IONnon-polymer23.03Chemie (NA)
7J, K, L, M
(A)
CHLORIDE IONnon-polymer35.54Chemie (CL)
8N
(A)
2'-DEOXYGUANOSINE-5'-TRIPHOSPHATEnon-polymer507.21Chemie (DGT)
9O, P, Q, R
(T, P, D, A)
waterwater18.0394Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight47648.9
Non-Polymers*Number of molecules10
Total formula weight766.6
All*Total formula weight48415.5
*Water molecules are not included.

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PDB entries from 2025-06-11

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