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6NJE

Crystal structure of the motor domain of human kinesin family member 22

Replaces:  3BFN
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Kinesin-like protein KIF22polymer37942132.81UniProt (Q14807)
Pfam (PF00225)
Homo sapiens (Human)Kinesin-like DNA-binding protein,Kinesin-like protein 4
2B
(A)
MAGNESIUM IONnon-polymer24.31Chemie (MG)
3C
(A)
ADENOSINE-5'-DIPHOSPHATEnon-polymer427.21Chemie (ADP)
4D, E, F
(A)
CHLORIDE IONnon-polymer35.53Chemie (CL)
5G
(A)
SODIUM IONnon-polymer23.01Chemie (NA)
6H
(A)
waterwater18.090Chemie (HOH)
Sequence modifications
A: 40 - 400 (UniProt: Q14807)
PDBExternal DatabaseDetails
Met 22-initiating methionine
His 23-expression tag
His 24-expression tag
His 25-expression tag
His 26-expression tag
His 27-expression tag
His 28-expression tag
Ser 29-expression tag
Ser 30-expression tag
Gly 31-expression tag
Arg 32-expression tag
Glu 33-expression tag
Asn 34-expression tag
Leu 35-expression tag
Tyr 36-expression tag
Phe 37-expression tag
Gln 38-expression tag
Gly 39-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight42132.8
Non-Polymers*Number of molecules6
Total formula weight580.9
All*Total formula weight42713.7
*Water molecules are not included.

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PDB entries from 2026-02-18

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