6NJ5
Thermostable variant of human carbonic anhydrase II with disordered tetrazine 2.0 at site 233
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Carbonic anhydrase 2 | polymer | 266 | 30241.9 | 1 | UniProt (P00918) Pfam (PF00194) In PDB | Homo sapiens (Human) | Carbonate dehydratase II,Carbonic anhydrase C,CAC,Carbonic anhydrase II,CA-II |
2 | A | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
3 | water | water | 18.0 | 362 | Chemie (HOH) |
Sequence modifications
A: 2 - 260 (UniProt: P00918)
PDB | External Database | Details |
---|---|---|
Met 0 | - | initiating methionine |
Ala 1 | - | expression tag |
Thr 64 | Ala 65 | engineered mutation |
His 99 | Leu 100 | engineered mutation |
Asn 153 | Lys 153 | engineered mutation |
Ser 223 | Leu 223 | engineered mutation |
Djd 233 | Glu 233 | engineered mutation |
Pro 239 | Leu 239 | engineered mutation |
Thr 247 | Ala 247 | engineered mutation |
His 261 | - | expression tag |
His 262 | - | expression tag |
His 263 | - | expression tag |
His 264 | - | expression tag |
His 265 | - | expression tag |
His 266 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 30241.9 | |
Non-Polymers* | Number of molecules | 1 |
Total formula weight | 65.4 | |
All* | Total formula weight | 30307.3 |