6NH7
Structure of human endothelial nitric oxide synthase heme domain in complex with 6-(3-(3-(dimethylamino)propyl)-2,5,6-trifluorophenethyl)-4-methylpyridin-2-amine
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Endothelial nitric oxide synthase splice variant eNOS13A | polymer | 440 | 49345.8 | 2 | UniProt (A0S0A6) Pfam (PF02898) UniProt (by SIFTS) (P29474) In PDB | Homo sapiens (Human) | |
| 2 | A, B | PROTOPORPHYRIN IX CONTAINING FE | non-polymer | 616.5 | 2 | Chemie (HEM) | |||
| 3 | A, B | 6-(2-{3-[3-(dimethylamino)propyl]-2,5,6-trifluorophenyl}ethyl)-4-methylpyridin-2-amine | non-polymer | 351.4 | 4 | Chemie (KMM) | |||
| 4 | A, B | 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL | non-polymer | 209.2 | 7 | Chemie (BTB) | |||
| 5 | A | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 6 | A, B | GADOLINIUM ATOM | non-polymer | 157.3 | 4 | Chemie (GD) | |||
| 7 | water | water | 18.0 | 271 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 98691.5 | |
| Non-Polymers* | Number of molecules | 18 |
| Total formula weight | 4797.7 | |
| All* | Total formula weight | 103489.2 |
