6NH6
Structure of the human endothelial nitric oxide synthase heme domain in complex with 6-(3-(3-(dimethylamino)propyl)-2,6-difluorophenethyl)-4-methylpyridin-2-amine
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C, D | Endothelial nitric oxide synthase splice variant eNOS13A | polymer | 440 | 49345.8 | 4 | UniProt (A0S0A6) Pfam (PF02898) UniProt (by SIFTS) (P29474) In PDB | Homo sapiens (Human) | |
2 | A, D, B, C | PROTOPORPHYRIN IX CONTAINING FE | non-polymer | 616.5 | 4 | Chemie (HEM) | |||
3 | A, D, B, C | 5,6,7,8-TETRAHYDROBIOPTERIN | non-polymer | 241.2 | 4 | Chemie (H4B) | |||
4 | A, D, B, C | 6-(2-{3-[3-(dimethylamino)propyl]-2,6-difluorophenyl}ethyl)-4-methylpyridin-2-amine | non-polymer | 333.4 | 4 | Chemie (KL7) | |||
5 | C, A, D, B | 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL | non-polymer | 209.2 | 13 | Chemie (BTB) | |||
6 | C, A | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
7 | C, A | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
8 | C, A, D, B | CHLORIDE ION | non-polymer | 35.5 | 4 | Chemie (CL) | |||
9 | C, A, D, B | GADOLINIUM ATOM | non-polymer | 157.3 | 4 | Chemie (GD) | |||
10 | water | water | 18.0 | 623 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 197383.1 | |
Non-Polymers* | Number of molecules | 37 |
Total formula weight | 8570.5 | |
All* | Total formula weight | 205953.6 |