6NFG
CYCLIC GMP-AMP SYNTHASE in complex with compound 16 inhibitor: 7-hydroxy-N-methyl-5-phenylpyrazolo[1,5-a]pyrimidine-3-carboxamide
Replaces: 5V8HEntity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | CYCLIC GMP-AMP SYNTHASE | polymer | 362 | 42404.9 | 2 | UniProt (Q8N884) Pfam (PF03281) Pfam (PF20266) In PDB | Homo sapiens (Human) | h-cGAS,2'3'-cGAMP synthase,Mab-21 domain-containing protein 1 |
| 2 | A, B | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 3 | A, B | 7-hydroxy-N-methyl-5-phenylpyrazolo[1,5-a]pyrimidine-3-carboxamide | non-polymer | 268.3 | 2 | Chemie (KKP) | |||
| 4 | water | water | 18.0 | 177 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 84809.8 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 667.4 | |
| All* | Total formula weight | 85477.2 |
