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6NFE

Crystal Structure of Ribose-phosphate Pyrophosphokinase from Legionella pneumophila with bound AMP, ADP, and Ribose-5-Phosphate

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Ribose-phosphate pyrophosphokinasepolymer32335199.72UniProt (A0A2S6FBX1)
Pfam (PF13793)
Pfam (PF14572)
UniProt (by SIFTS) (Q5ZY30)
Legionella pneumophilaRPPK,5-phospho-D-ribosyl alpha-1-diphosphate,Phosphoribosyl diphosphate synthase,Phosphoribosyl pyrophosphate synthase,PRPPase
2C, F, I, K, L...
(A, B)
1,2-ETHANEDIOLnon-polymer62.111Chemie (EDO)
3D, G, U
(A, B)
ETHANOLnon-polymer46.13Chemie (EOH)
4E, T
(A, B)
5-O-phosphono-alpha-D-ribofuranosenon-polymer230.12Chemie (HSX)
5H, J
(A)
ADENOSINE MONOPHOSPHATEnon-polymer347.22Chemie (AMP)
PubChem (224)
PubChem (34768)
PubChem (83862)
PubChem (446048)
PubChem (515384)
PubChem (638042)
PubChem (5316444)
PubChem (5742864)
PubChem (12163610)
PubChem (12358355)
PubChem (16397049)
PubChem (16760266)
PubChem (40467049)
PubChem (40469468)
PubChem (44348067)
PubChem (45358029)
PubChem (46874558)
PubChem (40459109)
PubChem (46875232)
PubChem (177678969)
PubChem (6083)
PubChem (1549371)
PubChem (92144436)
PubChem (57358045)
PubChem (57879893)
PubChem (57879902)
PubChem (12358354)
PubChem (122197642)
PubChem (162290139)
PubChem (162946266)
PubChem (171699505)
6N, P
(A, B)
ADENOSINE-5'-DIPHOSPHATEnon-polymer427.22Chemie (ADP)
7W, X
(A, B)
waterwater18.0524Chemie (HOH)
Sequence modifications
A, B: 1 - 315 (UniProt: A0A2S6FBX1)
PDBExternal DatabaseDetails
Met -7-initiating methionine
Ala -6-expression tag
His -5-expression tag
His -4-expression tag
His -3-expression tag
His -2-expression tag
His -1-expression tag
His 0-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight70399.4
Non-Polymers*Number of molecules20
Total formula weight2830.0
All*Total formula weight73229.4
*Water molecules are not included.

251801

PDB entries from 2026-04-08

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