6NFE

Crystal Structure of Ribose-phosphate Pyrophosphokinase from Legionella pneumophila with bound AMP, ADP, and Ribose-5-Phosphate

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Ribose-phosphate pyrophosphokinase	polymer	323	35199.7	2	UniProt (A0A2S6FBX1) Pfam (PF13793) Pfam (PF14572) UniProt (by SIFTS) (Q5ZY30)	Legionella pneumophila	RPPK,5-phospho-D-ribosyl alpha-1-diphosphate,Phosphoribosyl diphosphate synthase,Phosphoribosyl pyrophosphate synthase,PRPPase
2	C, F, I, K, L... (A, B)	1,2-ETHANEDIOL	non-polymer		62.1	11	Chemie (EDO)
3	D, G, U (A, B)	ETHANOL	non-polymer		46.1	3	Chemie (EOH)
4	E, T (A, B)	5-O-phosphono-alpha-D-ribofuranose	non-polymer		230.1	2	Chemie (HSX)
5	H, J (A)	ADENOSINE MONOPHOSPHATE	non-polymer		347.2	2	Chemie (AMP)
6	N, P (A, B)	ADENOSINE-5'-DIPHOSPHATE	non-polymer		427.2	2	Chemie (ADP)
7	W, X (A, B)	water	water		18.0	524	Chemie (HOH)

Sequence modifications

A, B: 1 - 315 (UniProt: A0A2S6FBX1)

PDB	External Database	Details
Met -7	-	initiating methionine
Ala -6	-	expression tag
His -5	-	expression tag
His -4	-	expression tag
His -3	-	expression tag
His -2	-	expression tag
His -1	-	expression tag
His 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	70399.4
Non-Polymers*	Number of molecules	20
	Total formula weight	2830.0
All*	Total formula weight	73229.4

*Water molecules are not included.