6NE2
Designed repeat protein in complex with Fz7
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (B) | Designed repeat protein binder | polymer | 200 | 20933.8 | 1 | Escherichia coli | ||
| 2 | B (A) | Frizzled-7 | polymer | 124 | 14111.2 | 1 | UniProt (O75084) Pfam (PF01392) | Homo sapiens (Human) | hFz7,FzE3 |
| 3 | C, D, E, F, G... (B, A) | ACETATE ION | non-polymer | 59.0 | 9 | Chemie (ACT) | |||
| 4 | H, I, J, K, L... (B, A) | SULFATE ION | non-polymer | 96.1 | 10 | Chemie (SO4) | |||
| 5 | M, N (B) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 2 | Chemie (EDO) | |||
| 6 | O (A) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 1 | Chemie (NAG) | |||
| 7 | Y, Z (B, A) | water | water | 18.0 | 268 | Chemie (HOH) |
Sequence modifications
A: 1 - 118 (UniProt: O75084)
| PDB | External Database | Details |
|---|---|---|
| His 119 | - | expression tag |
| His 120 | - | expression tag |
| His 121 | - | expression tag |
| His 122 | - | expression tag |
| His 123 | - | expression tag |
| His 124 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 35045.0 | |
| Non-Polymers* | Number of molecules | 22 |
| Total formula weight | 1837.4 | |
| All* | Total formula weight | 36882.4 |
