6ND2
Staphylococcus aureus Dihydrofolate Reductase complexed with NADPH and 6-ETHYL-5-[(3R)-3-[2-METHOXY-5-(PYRIDIN-4-YL)PHENYL]BUT-1-YN-1-YL]PYRIMIDINE-2,4-DIAMINE (UCP1063)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (X) | Dihydrofolate reductase | polymer | 157 | 18015.6 | 1 | UniProt (P0A017) Pfam (PF00186) | Staphylococcus aureus | DHFR |
| 2 | B (X) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 3 | C (X) | 6-ethyl-5-{(3S)-3-[2-methoxy-5-(pyridin-4-yl)phenyl]but-1-yn-1-yl}pyrimidine-2,4-diamine | non-polymer | 373.5 | 1 | Chemie (G8J) | |||
| 4 | D (X) | Tricyclic NADPH | non-polymer | 745.4 | 1 | Chemie (XNP) | |||
| 5 | E (X) | water | water | 18.0 | 37 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 18015.6 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 1211.0 | |
| All* | Total formula weight | 19226.5 |
