6NC2

AMC011 v4.2 SOSIP Env trimer in complex with fusion peptide targeting antibody ACS202 fragment antigen binding

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C, D, E, F...	AMC011 v4.2 SOSIP gp120	polymer	512	57668.9	6		Human immunodeficiency virus 1
2	B, I, J, K, M...	AMC011 v4.2 SOSIP gp41	polymer	153	17300.7	6	Pfam (PF00517) UniProt (by SIFTS) (Q78156) In PDB	Human immunodeficiency virus 1
3	H, O, P, Q, R...	Monoclonal antibody ACS202 fragment antigen binding heavy chain	polymer	254	27392.0	6		Homo sapiens (human)
4	L, T, U, V, W...	Monoclonal antibody ACS202 fragment antigen binding kappa chain	polymer	233	25475.7	6		Homo sapiens (human)
5	b, c, f, g, j...	alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		910.8	12	In PDB GlyTouCan (G22768VO)
6	d, h, l, p, t...	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		424.4	6	In PDB GlyTouCan (G42666HT)
7	a, e, i, m, q...	alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		1073.0	6	In PDB GlyTouCan (G56014GC)
8	B, C, I, D, J...	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	30	Chemie (NAG)

Contents of the asymmetric unit

Polymers	Number of chains	24
	Total formula weight	767023.7
Branched	Number of molecules	24
	Total formula weight	19914.1
Non-Polymers*	Number of molecules	30
	Total formula weight	6636.2
All*	Total formula weight	793574.0

*Water molecules are not included.