6NBS
WT ERK2 with compound 2507-8
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Mitogen-activated protein kinase 1 | polymer | 367 | 42432.8 | 1 | UniProt (P63086) Pfam (PF00069) UniProt (by SIFTS) (P28482) | Rattus norvegicus (Rat) | MAP kinase 1,MAPK 1,ERT1,Extracellular signal-regulated kinase 2,ERK-2,MAP kinase isoform p42,p42-MAPK,Mitogen-activated protein kinase 2,MAP kinase 2,MAPK 2 |
| 2 | B (A) | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 3 | C (A) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 4 | D (A) | (5S)-5-benzyl-4,5-dihydro-1H-imidazol-2-amine | non-polymer | 175.2 | 1 | Chemie (KJ7) | |||
| 5 | E (A) | N-{3-[(2Z,4S)-1-(2-{[2-(2-amino-1H-imidazol-1-yl)ethyl](methyl)amino}ethyl)-3-(3-cyclohexylpropyl)-2-iminoimidazolidin-4-yl]propyl}guanidine | non-polymer | 474.7 | 1 | Chemie (KJ4) | |||
| 6 | F (A) | water | water | 18.0 | 208 | Chemie (HOH) |
Sequence modifications
A: 1 - 358 (UniProt: P63086)
| PDB | External Database | Details |
|---|---|---|
| Met -8 | - | expression tag |
| Ala -7 | - | expression tag |
| His -6 | - | expression tag |
| His -5 | - | expression tag |
| His -4 | - | expression tag |
| His -3 | - | expression tag |
| His -2 | - | expression tag |
| His -1 | - | expression tag |
| Ala 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 42432.8 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 838.1 | |
| All* | Total formula weight | 43270.9 |
