6N91

Crystal Structure of Adenosine Deaminase from Vibrio cholerae Complexed with Pentostatin (Deoxycoformycin)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Adenosine deaminase	polymer	340	37274.3	2	UniProt (Q9KNI7) Pfam (PF00962)	Vibrio cholerae O1 biovar El Tor str. N16961	Adenosine aminohydrolase
2	C, J (A, B)	2'-DEOXYCOFORMYCIN	non-polymer		268.3	2	Chemie (DCF)
3	D, K (A, B)	ZINC ION	non-polymer		65.4	2	Chemie (ZN)
4	E, L, R (A, B)	3-CYCLOHEXYL-1-PROPYLSULFONIC ACID	non-polymer		221.3	3	Chemie (CXS)
5	F, M (A, B)	FORMIC ACID	non-polymer		46.0	2	Chemie (FMT)
6	G (A)	SULFATE ION	non-polymer		96.1	1	Chemie (SO4)
7	H, Q (A, B)	PHOSPHATE ION	non-polymer		95.0	2	Chemie (PO4)
8	I, P (A, B)	GLYCEROL	non-polymer		92.1	2	Chemie (GOL)
9	N (B)	SODIUM ION	non-polymer		23.0	1	Chemie (NA)
10	O (B)	1,2-ETHANEDIOL	non-polymer		62.1	1	Chemie (EDO)
11	S, T (A, B)	water	water		18.0	385	Chemie (HOH)

Sequence modifications

A, B: 1 - 334 (UniProt: Q9KNI7)

PDB	External Database	Details
His 335	-	expression tag
His 336	-	expression tag
His 337	-	expression tag
His 338	-	expression tag
His 339	-	expression tag
His 340	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	74548.6
Non-Polymers*	Number of molecules	16
	Total formula weight	1978.6
All*	Total formula weight	76527.2

*Water molecules are not included.