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6N81

Crystal structure of GII.4 2002 norovirus P domain in complex with cross-reactive human antibody A1227

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Major capsid proteinpolymer30933940.82UniProt (R4I4P2)
Pfam (PF08435)
Norovirus Hu/GII.4/Farmington Hills/2004/USA
2C, F
(D, L)
A1227 Fab light chainpolymer21423309.72Homo sapiens (human)
3D, E
(C, H)
A1227 Fab heavy chainpolymer23624710.82Homo sapiens (human)
4G, H, I, J, K...
(A, B, D, C, H...)
waterwater18.0307Chemie (HOH)
Sequence modifications
A, B: 225 - 530 (UniProt: R4I4P2)
PDBExternal DatabaseDetails
Gly 222-expression tag
Pro 223-expression tag
Ser 224-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains6
Total formula weight163922.7
All*Total formula weight163922.7
*Water molecules are not included.

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PDB entries from 2025-12-24

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