6N6V
OXA-23 mutant F110A/M221A low pH form meropenem complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Beta-lactamase | polymer | 242 | 27382.6 | 1 | UniProt (Q9L4P2) Pfam (PF00905) | Acinetobacter baumannii | Beta-lactamase oxa23,BlaOXA-23,Carbapenemase OXA-23,Class D beta-lactamase,OXA-23,OXA-23 class D beta-lactamase,OXA23 carbapenemase,class D Beta-lactamase Oxa-23 |
| 2 | B (A) | meropenem, bound form | non-polymer | 385.5 | 1 | Chemie (KE1) | |||
| 3 | C (A) | water | water | 18.0 | 166 | Chemie (HOH) |
Sequence modifications
A: 32 - 273 (UniProt: Q9L4P2)
| PDB | External Database | Details |
|---|---|---|
| Ala 110 | Phe 110 | engineered mutation |
| Ala 221 | Met 221 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 27382.6 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 385.5 | |
| All* | Total formula weight | 27768.1 |
