6N4X

Metabotropic Glutamate Receptor 5 Apo Form Ligand Binding Domain

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Metabotropic glutamate receptor 5	polymer	877	98506.8	2	UniProt (P41594) Pfam (PF01094) Pfam (PF07562) Pfam (PF00003)	Homo sapiens (Human)	mGluR5
2	C, D, E, F, H... (A, B)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	6	Chemie (NAG)
3	G (B)	MAGNESIUM ION	non-polymer		24.3	1	Chemie (MG)

Sequence modifications

A, B: 20 - 865 (UniProt: P41594)

PDB	External Database	Details
Met -5	-	initiating methionine
Lys -4	-	expression tag
Thr -3	-	expression tag
Ile -2	-	expression tag
Ile -1	-	expression tag
Ala 0	-	expression tag
Leu 1	-	expression tag
Ser 2	-	expression tag
Tyr 3	-	expression tag
Ile 4	-	expression tag
Phe 5	-	expression tag
Cys 6	-	expression tag
Leu 7	-	expression tag
Val 8	-	expression tag
Phe 9	-	expression tag
Ala 10	-	expression tag
Asp 11	-	expression tag
Tyr 12	-	expression tag
Lys 13	-	expression tag
Asp 14	-	expression tag
Asp 15	-	expression tag
Asp 16	-	expression tag
Asp 17	-	expression tag
Ala 18	-	expression tag
Ala 19	-	expression tag
His 866	-	expression tag
His 867	-	expression tag
His 868	-	expression tag
His 869	-	expression tag
His 870	-	expression tag
His 871	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	197013.7
Non-Polymers*	Number of molecules	7
	Total formula weight	1351.6
All*	Total formula weight	198365.2

*Water molecules are not included.