6N4B
Cannabinoid Receptor 1-G Protein Complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Guanine nucleotide-binding protein G(i) subunit alpha-1 | polymer | 354 | 40415.0 | 1 | UniProt (P63096) Pfam (PF00503) | Homo sapiens (Human) | Adenylate cyclase-inhibiting G alpha protein |
| 2 | B (B) | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 | polymer | 344 | 37671.1 | 1 | UniProt (P62873) Pfam (PF25391) | Homo sapiens (Human) | Transducin beta chain 1 |
| 3 | C (C) | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 | polymer | 71 | 7861.1 | 1 | UniProt (P59768) Pfam (PF00631) | Homo sapiens (Human) | G gamma-I |
| 4 | D (R) | Cannabinoid receptor 1 | polymer | 495 | 55678.5 | 1 | UniProt (P21554) Pfam (PF00001) | Homo sapiens (Human) | CB1,CANN6 |
| 5 | E (S) | scFv16 | polymer | 259 | 27784.9 | 1 | Mus musculus (Mouse) | ||
| 6 | F (R) | methyl N-{1-[(4-fluorophenyl)methyl]-1H-indazole-3-carbonyl}-3-methyl-L-valinate | non-polymer | 397.4 | 1 | Chemie (KCA) PubChem (119025665) PubChem (122208372) | |||
| 7 | G, H (R) | CHOLESTEROL | non-polymer | 386.7 | 2 | Chemie (CLR) PubChem (304) PubChem (191463) PubChem (368063) PubChem (369319) PubChem (638019) PubChem (1549081) PubChem (1553803) PubChem (5283629) PubChem (5284644) PubChem (5315842) PubChem (6419195) PubChem (6994560) PubChem (7055705) PubChem (7055706) PubChem (7059398) PubChem (7059400) PubChem (7059635) PubChem (7103033) PubChem (7182477) PubChem (7182478) PubChem (9909206) PubChem (10045721) PubChem (71168115) PubChem (10134774) PubChem (10293553) PubChem (71173031) PubChem (11003580) PubChem (11025495) PubChem (11058155) PubChem (11463329) PubChem (11868624) PubChem (11868625) PubChem (11869366) PubChem (11869367) PubChem (11869368) PubChem (11869369) PubChem (12120344) PubChem (12156156) PubChem (12303135) PubChem (12303148) PubChem (12303156) PubChem (12303159) PubChem (12303160) PubChem (16219173) PubChem (16758052) PubChem (40477506) PubChem (40557614) PubChem (42579431) PubChem (42579432) PubChem (176980071) PubChem (45044259) PubChem (18640088) PubChem (1715243) PubChem (1715244) PubChem (23423981) PubChem (49853509) PubChem (44654663) PubChem (46937002) PubChem (59274407) PubChem (50990013) PubChem (68311425) PubChem (68311398) PubChem (143173313) PubChem (177156123) PubChem (5997) PubChem (1551269) PubChem (90070115) PubChem (52934537) PubChem (117965027) PubChem (6432564) PubChem (6710666) PubChem (124146240) PubChem (56621683) PubChem (7059399) PubChem (124897607) PubChem (124896959) PubChem (10861996) PubChem (132837164) PubChem (11834483) PubChem (11888915) PubChem (11888914) PubChem (57915018) PubChem (57939063) PubChem (138967089) PubChem (58428240) PubChem (58445498) PubChem (139566851) PubChem (58663286) PubChem (15939944) PubChem (59450329) PubChem (59628412) PubChem (171828367) PubChem (173516975) PubChem (59965215) PubChem (71234641) PubChem (59993755) PubChem (60001463) PubChem (66634651) PubChem (68055877) PubChem (68166463) PubChem (68315613) PubChem (70795838) PubChem (70797612) PubChem (70954610) PubChem (70957185) PubChem (71463909) PubChem (89951918) PubChem (90224410) PubChem (91298236) PubChem (101624109) PubChem (124225449) PubChem (124429284) PubChem (124909223) PubChem (124909224) PubChem (124909225) PubChem (130459183) PubChem (131992107) PubChem (139568882) PubChem (142983773) PubChem (144054483) PubChem (144209461) PubChem (144331236) PubChem (144808354) PubChem (145053568) PubChem (145157652) PubChem (145215073) PubChem (145230478) PubChem (146320991) PubChem (147857230) PubChem (154993519) PubChem (158603858) PubChem (162906452) PubChem (162906453) PubChem (162906454) PubChem (162906455) PubChem (162906456) PubChem (162906457) PubChem (163255768) PubChem (163389210) PubChem (164665303) PubChem (166553771) PubChem (166712004) PubChem (170116175) PubChem (171764280) PubChem (171817101) PubChem (171817104) PubChem (174285573) |
Sequence modifications
B: 2 - 340 (UniProt: P62873)
R: -6 - 472 (UniProt: P21554)
| PDB | External Database | Details |
|---|---|---|
| Pro -3 | - | expression tag |
| Gly -2 | - | expression tag |
| Ser -1 | - | expression tag |
| Ser 0 | - | expression tag |
| Gly 1 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Asp -14 | - | expression tag |
| Tyr -13 | - | expression tag |
| Lys -12 | - | expression tag |
| Asp -11 | - | expression tag |
| Asp -10 | - | expression tag |
| Asp -9 | - | expression tag |
| Asp -8 | - | expression tag |
| Ala -7 | - | expression tag |
| Glu 81 | - | insertion |
| Asn 82 | - | insertion |
| Leu 83 | - | insertion |
| Tyr 84 | - | insertion |
| Phe 85 | - | insertion |
| Gln 86 | - | insertion |
| Gly 87 | - | insertion |
| Gly 473 | - | expression tag |
| Ser 474 | - | expression tag |
| His 475 | - | expression tag |
| His 476 | - | expression tag |
| His 477 | - | expression tag |
| His 478 | - | expression tag |
| His 479 | - | expression tag |
| His 480 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 169410.7 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 1170.8 | |
| All* | Total formula weight | 170581.5 |
