6N4B
Cannabinoid Receptor 1-G Protein Complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Guanine nucleotide-binding protein G(i) subunit alpha-1 | polymer | 354 | 40415.0 | 1 | UniProt (P63096) Pfam (PF00503) | Homo sapiens (Human) | Adenylate cyclase-inhibiting G alpha protein |
| 2 | B (B) | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 | polymer | 344 | 37671.1 | 1 | UniProt (P62873) Pfam (PF00400) | Homo sapiens (Human) | Transducin beta chain 1 |
| 3 | C (C) | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 | polymer | 71 | 7861.1 | 1 | UniProt (P59768) Pfam (PF00631) | Homo sapiens (Human) | G gamma-I |
| 4 | D (R) | Cannabinoid receptor 1 | polymer | 495 | 55678.5 | 1 | UniProt (P21554) Pfam (PF00001) | Homo sapiens (Human) | CB1,CANN6 |
| 5 | E (S) | scFv16 | polymer | 259 | 27784.9 | 1 | Mus musculus (Mouse) | ||
| 6 | F (R) | methyl N-{1-[(4-fluorophenyl)methyl]-1H-indazole-3-carbonyl}-3-methyl-L-valinate | non-polymer | 397.4 | 1 | Chemie (KCA) | |||
| 7 | G, H (R) | CHOLESTEROL | non-polymer | 386.7 | 2 | Chemie (CLR) |
Sequence modifications
B: 2 - 340 (UniProt: P62873)
R: -6 - 472 (UniProt: P21554)
| PDB | External Database | Details |
|---|---|---|
| Pro -3 | - | expression tag |
| Gly -2 | - | expression tag |
| Ser -1 | - | expression tag |
| Ser 0 | - | expression tag |
| Gly 1 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Asp -14 | - | expression tag |
| Tyr -13 | - | expression tag |
| Lys -12 | - | expression tag |
| Asp -11 | - | expression tag |
| Asp -10 | - | expression tag |
| Asp -9 | - | expression tag |
| Asp -8 | - | expression tag |
| Ala -7 | - | expression tag |
| Glu 81 | - | insertion |
| Asn 82 | - | insertion |
| Leu 83 | - | insertion |
| Tyr 84 | - | insertion |
| Phe 85 | - | insertion |
| Gln 86 | - | insertion |
| Gly 87 | - | insertion |
| Gly 473 | - | expression tag |
| Ser 474 | - | expression tag |
| His 475 | - | expression tag |
| His 476 | - | expression tag |
| His 477 | - | expression tag |
| His 478 | - | expression tag |
| His 479 | - | expression tag |
| His 480 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 169410.7 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 1170.8 | |
| All* | Total formula weight | 170581.5 |
