6N4B
Cannabinoid Receptor 1-G Protein Complex
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Guanine nucleotide-binding protein G(i) subunit alpha-1 | polymer | 354 | 40415.0 | 1 | UniProt (P63096) Pfam (PF00503) In PDB | Homo sapiens (Human) | Adenylate cyclase-inhibiting G alpha protein |
2 | B | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 | polymer | 344 | 37671.1 | 1 | UniProt (P62873) Pfam (PF00400) In PDB | Homo sapiens (Human) | Transducin beta chain 1 |
3 | C | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 | polymer | 71 | 7861.1 | 1 | UniProt (P59768) Pfam (PF00631) In PDB | Homo sapiens (Human) | G gamma-I |
4 | R | Cannabinoid receptor 1 | polymer | 495 | 55678.5 | 1 | UniProt (P21554) Pfam (PF00001) In PDB | Homo sapiens (Human) | CB1,CANN6 |
5 | S | scFv16 | polymer | 259 | 27784.9 | 1 | Mus musculus (Mouse) | ||
6 | R | methyl N-{1-[(4-fluorophenyl)methyl]-1H-indazole-3-carbonyl}-3-methyl-L-valinate | non-polymer | 397.4 | 1 | Chemie (KCA) | |||
7 | R | CHOLESTEROL | non-polymer | 386.7 | 2 | Chemie (CLR) |
Sequence modifications
B: 2 - 340 (UniProt: P62873)
R: -6 - 472 (UniProt: P21554)
PDB | External Database | Details |
---|---|---|
Pro -3 | - | expression tag |
Gly -2 | - | expression tag |
Ser -1 | - | expression tag |
Ser 0 | - | expression tag |
Gly 1 | - | expression tag |
PDB | External Database | Details |
---|---|---|
Asp -14 | - | expression tag |
Tyr -13 | - | expression tag |
Lys -12 | - | expression tag |
Asp -11 | - | expression tag |
Asp -10 | - | expression tag |
Asp -9 | - | expression tag |
Asp -8 | - | expression tag |
Ala -7 | - | expression tag |
Glu 81 | - | insertion |
Asn 82 | - | insertion |
Leu 83 | - | insertion |
Tyr 84 | - | insertion |
Phe 85 | - | insertion |
Gln 86 | - | insertion |
Gly 87 | - | insertion |
Gly 473 | - | expression tag |
Ser 474 | - | expression tag |
His 475 | - | expression tag |
His 476 | - | expression tag |
His 477 | - | expression tag |
His 478 | - | expression tag |
His 479 | - | expression tag |
His 480 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 5 |
Total formula weight | 169410.7 | |
Non-Polymers* | Number of molecules | 3 |
Total formula weight | 1170.8 | |
All* | Total formula weight | 170581.5 |