6N3G
Crystal structure of histone lysine methyltransferase SmyD2 in complex with polyethylene glycol
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | N-lysine methyltransferase SMYD2 | polymer | 433 | 49832.2 | 1 | UniProt (Q9NRG4) Pfam (PF00856) Pfam (PF01753) | Homo sapiens (Human) | HSKM-B,Histone methyltransferase SMYD2,Lysine N-methyltransferase 3C,SET and MYND domain-containing protein 2 |
| 2 | B (A) | S-ADENOSYL-L-HOMOCYSTEINE | non-polymer | 384.4 | 1 | Chemie (SAH) | |||
| 3 | C (A) | DODECAETHYLENE GLYCOL | non-polymer | 546.6 | 1 | Chemie (12P) | |||
| 4 | D, E (A) | NICKEL (II) ION | non-polymer | 58.7 | 2 | Chemie (NI) | |||
| 5 | F, G, H, I, J (A) | ETHANOL | non-polymer | 46.1 | 5 | Chemie (EOH) | |||
| 6 | K, L, M (A) | ZINC ION | non-polymer | 65.4 | 3 | Chemie (ZN) | |||
| 7 | N (A) | water | water | 18.0 | 79 | Chemie (HOH) |
Sequence modifications
A: 1 - 433 (UniProt: Q9NRG4)
| PDB | External Database | Details |
|---|---|---|
| Glu 165 | Gly 165 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 49832.2 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 1475.0 | |
| All* | Total formula weight | 51307.2 |
