6N17
Crystal structure of Tdp1 catalytic domain in complex with compound XZ577
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Tyrosyl-DNA phosphodiesterase 1 | polymer | 461 | 52126.3 | 2 | UniProt (Q9NUW8) Pfam (PF06087) | Homo sapiens (Human) | Tyr-DNA phosphodiesterase 1 |
| 2 | C, G (A, B) | 4-[(3-carboxypropanoyl)amino]benzene-1,2-dicarboxylic acid | non-polymer | 281.2 | 2 | Chemie (K8Y) | |||
| 3 | D, E, H, I, J (A, B) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 5 | Chemie (EDO) | |||
| 4 | F (A) | DIMETHYL SULFOXIDE | non-polymer | 78.1 | 1 | Chemie (DMS) | |||
| 5 | K, L (A, B) | water | water | 18.0 | 842 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 104252.7 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 950.9 | |
| All* | Total formula weight | 105203.6 |
