6N0P
BRAF in complex with N-(3-(2-(2-hydroxyethoxy)-6-morpholinopyridin-4-yl)-4-methylphenyl)-2-(trifluoromethyl)isonicotinamide (LXH254)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Serine/threonine-protein kinase B-raf | polymer | 273 | 31139.1 | 2 | UniProt (P15056) Pfam (PF07714) | Homo sapiens (Human) | Proto-oncogene B-Raf,p94,v-Raf murine sarcoma viral oncogene homolog B1 |
| 2 | C, D (A, B) | N-{3-[2-(2-hydroxyethoxy)-6-(morpholin-4-yl)pyridin-4-yl]-4-methylphenyl}-2-(trifluoromethyl)pyridine-4-carboxamide | non-polymer | 502.5 | 2 | Chemie (K81) | |||
| 3 | E, F (A, B) | water | water | 18.0 | 337 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 62278.3 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 1005.0 | |
| All* | Total formula weight | 63283.2 |
