6MYY
Germline VRC01 antibody recognition of a modified clade C HIV-1 envelope trimer, 3 Fabs bound, sharpened map
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, E | 426c DS-SOSIP D3 | polymer | 626 | 70243.8 | 3 | Pfam (PF00516) Pfam (PF00517) UniProt (by SIFTS) (Q2N0S9) UniProt (by SIFTS) (M4Q8P8) In PDB | Human immunodeficiency virus 1 (HIV-1) | |
| 2 | L, C, F | VRC01GL light chain | polymer | 229 | 25008.9 | 3 | UniProt (Q6PJF2) Pfam (PF07686) Pfam (PF07654) In PDB | Homo sapiens (Human) | |
| 3 | H, D, G | VRC01GL heavy chain | polymer | 233 | 25334.3 | 3 | UniProt (S6C4S0) Pfam (PF07686) Pfam (PF07654) In PDB | Homo sapiens (Human) | |
| 4 | g, i, I, j, J... | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 18 | In PDB GlyTouCan (G42666HT) | |||
| 5 | K, n, Z | alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 910.8 | 3 | In PDB GlyTouCan (G22768VO) | |||
| 6 | a, M, o | alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 1073.0 | 3 | In PDB GlyTouCan (G09724ZC) | |||
| 7 | b, d, e, N, P... | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 9 | In PDB GlyTouCan (G15407YE) | |||
| 8 | c, O, q | alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 1235.1 | 3 | In PDB GlyTouCan (G07617FP) | |||
| 9 | f, R, t | alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 748.7 | 3 | In PDB GlyTouCan (G81315DD) | |||
| 10 | h, T, v | alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 910.8 | 3 | In PDB GlyTouCan (G42227JK) | |||
| 11 | A, B, E | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 12 | Chemie (NAG) |
Sequence modifications
L, C, F: -18 - 107 (PDB: 6MYY)
L, C, F: 108 - 216 (UniProt: Q6PJF2)
H, D, G: 1 - 102 (PDB: 6MYY)
H, D, G: 103 - 219 (UniProt: S6C4S0)
L, C, F: 108 - 216 (UniProt: Q6PJF2)
H, D, G: 1 - 102 (PDB: 6MYY)
H, D, G: 103 - 219 (UniProt: S6C4S0)
| PDB | External Database | Details |
|---|---|---|
| His 220 | - | expression tag |
| His 221 | - | expression tag |
| His 222 | - | expression tag |
| His 223 | - | expression tag |
| His 224 | - | expression tag |
| His 225 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 9 |
| Total formula weight | 361761.1 | |
| Branched | Number of molecules | 42 |
| Total formula weight | 27553.3 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 2654.5 | |
| All* | Total formula weight | 391968.9 |
