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6MYN

Crystal structure of murine NF-kappaB inducing kinase (NIK) bound to inhibitor R7

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, BMitogen-activated protein kinase kinase kinase 14polymer34738399.32UniProt (Q9WUL6)
Pfam (PF00069)
In PDB
Mus musculus (Mouse)NF-kappa-beta-inducing kinase,Serine/threonine-protein kinase NIK
2A, BSULFATE IONnon-polymer96.15Chemie (SO4)
3A, B(5s,7s)-9-fluoro-10-[(3R)-3-hydroxy-3-(5-methyl-1,2-oxazol-3-yl)but-1-yn-1-yl]-N~3~-methyl-6,7-dihydro-5H-5,7-methanoimidazo[2,1-a][2]benzazepine-2,3-dicarboxamidenon-polymer463.52Chemie (K6Y)
4waterwater18.0105Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight76798.6
Non-Polymers*Number of molecules7
Total formula weight1407.2
All*Total formula weight78205.9
*Water molecules are not included.

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PDB entries from 2024-06-12

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