6MYN

Crystal structure of murine NF-kappaB inducing kinase (NIK) bound to inhibitor R7

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Mitogen-activated protein kinase kinase kinase 14	polymer	347	38399.3	2	UniProt (Q9WUL6) Pfam (PF00069)	Mus musculus (Mouse)	NF-kappa-beta-inducing kinase,Serine/threonine-protein kinase NIK
2	C, D, F, G, H (A, B)	SULFATE ION	non-polymer		96.1	5	Chemie (SO4)
3	E, I (A, B)	(5s,7s)-9-fluoro-10-[(3R)-3-hydroxy-3-(5-methyl-1,2-oxazol-3-yl)but-1-yn-1-yl]-N~3~-methyl-6,7-dihydro-5H-5,7-methanoimidazo[2,1-a][2]benzazepine-2,3-dicarboxamide	non-polymer		463.5	2	Chemie (K6Y)
4	J, K (A, B)	water	water		18.0	105	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	76798.6
Non-Polymers*	Number of molecules	7
	Total formula weight	1407.2
All*	Total formula weight	78205.9

*Water molecules are not included.